The most important combinations to remember are those that involve saving a file, quitting an application and shutting down your computer. Some combinations are great with editing should you desire to continue working even without a mouse. Following are the most basic combinations that are commonly used within a keyboard:CTRL + S : Saves FileCTRL + F4 : Quit ApplicationCTRL + ESC : Brings to “Start Menu”ALT + Tab : Shift from Application to ApplicationShift + Delete : Deletes File PermanentlySo the next time your mouse conks out on you, do not fret. Take a deep breath and be thankful your keyboard is still around and well.